BDBM21363 12-chloro-9-(2-fluorophenyl)-3-methyl-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,8,11,13-hexaene::8-chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine::CHEMBL655::Dormicum::Midazolam::Ro 21-3981::US20230416258, Compound Midazolam
SMILES Cc1ncc2CN=C(c3ccccc3F)c3cc(Cl)ccc3-n12
InChI Key InChIKey=DDLIGBOFAVUZHB-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 21363
Affinity DataKi: 2.47E+3nMAssay Description:Inhibition of human recombinant CYP3A4 in liver microsomes by mechanism based inhibition assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomeMore data for this Ligand-Target Pair
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human cytochrome P450 3A4More data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Inhibition of CYP3A4M (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:Inhibition of CYP3A4M in human liver microsomes incubated for 15 to 40 mins in presence of NADPHMore data for this Ligand-Target Pair